aetiology with respect to frequency
Last reviewed 01/2018
Inherited and acquired factors both contribute to the development of GORD (1)
- the prevalence of reflux symptoms is high in the parents of affected people
- concordance of reflux disease is higher in identical twin pairs
- genetic factors contribute about 18-31% to the cause of GORD
Common associated conditions are:
- sliding hiatus hernia
- pyloric stenosis
- pregnancy
Less common associations are:
- diabetic neuropathy
- scleroderma
Study evidence has emphasized the significance of lifestyle factors (1)
- these predisposing lifestyle
factors include:
- obesity
- smoking
- alcohol
- large, late meals (1)
Reference: