Ca125 (Ca - 125) - NICE urgent cancer referral guidance

Last reviewed 03/2023

 

Investigation findings and specific features Possible Cancer Recommendation
Serum CA125 results Ovarian

If serum CA125 is 35 IU/ml or greater, arrange an ultrasound scan of the abdomen and pelvis

  • normal serum CA125 (less than 35 IU/ ml), or CA125 of 35 IU/ml or greater but a normal ultrasound:
    • assess her carefully for other clinical causes of her symptoms and investigate if appropriate
    • if no other clinical cause is apparent, advise her to return to her GP if her symptoms become more frequent and/or persistent

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