spironolactone in hypertension
Last edited 08/2021 and last reviewed 08/2021
- suggested to add a low dose of spironolactone as the 4th line agent in hypertension management in those whose serum potassium is <4.5 mmol/L and whose eGFR is >45 ml/min/1.73m2 to achieve BP targets
- avoid use with K+ supplements, other K+-sparing diuretics, or significant renal dysfunction
Reference:
NICE guidance - management of hypertension in adults in primary care