investigations and management
Last reviewed 01/2018
Investigations include:
- blood tests - FBC; ESR; U+Es; LFTs; CRP; immunoglobulins; serum electrophoresis; complement (C3,C4); autoantibodies - antinuclear antibody (ANA), antineutrophil cytoplasmic antibody (ANCA), anti-double stranded DNA (anti-dsDNA), anti-glomerular basement membrane (anti-GBM); HBsAg; antiHCV;anti-streptolysin O titre (ASOT); blood culture
- urine analysis, microscopy (red cell casts - may also be dysmorphic red cells) and culture
- urine collection - 24 hour collection for creatinine clearance and protein excretion
- radiological investigation - renal ultrasound, chest Xray
- renal biopsy