type III cryoglobulin

Last reviewed 01/2018

Type III cryoglobulins are a polyclonal cryoglobulin in association with a polyclonal rheumatoid factor. The immunoglobulin composition include:

  • IgM-IgG
  • IgM-IgG-IgA

The clinical associations with a type III cryoglobulinaemia include:

  • SLE
  • rheumatoid arthritis
  • EBV
  • Sjogren's disease
  • CMV
  • hepatitis B
  • infective endocarditis
  • Kala-azar
  • leprosy
  • primary biliary cirrhosis
  • post-streptococcal nephritis