contra-indications and warnings for methotrexate
Last reviewed 01/2018
- pregnancy and lactation
- gross renal or hepatic disease or high alcohol intake
- pre-existing lung disease
- blood dyscrasia
- teratogenesis - stop 90 days before possible conception
- reduced male fertility
- care with drugs including: sulphonamides, co-trimoxazole, diuretics, azathioprine, phenytoin, NSAIDs, Trimethoprim, Probenecid