clinical features

Last reviewed 01/2018

Patients are usually in their early 20's.

Painful pruritus generally precedes the appearance of the lesions (1).

Eruption is usually symmetrical and begins in the emotional sweat areas - palms, soles, and sides and dorsum of digits. Severe eruption may spread to the backs of the hands and feet, and to the limbs.

The vesicles are translucent, deeply set and intensely itchy. They may have a "frog spawn" appearance. Vesicles may progress to bullae (1).

Attacks may be precipitated by heat or emotion.

Desquamation, inflammation, and secondary infection are some of the usual complications (1).

The condition generally subsides spontaneously within two to three weeks (1).

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