hepatic jaundice

Last reviewed 01/2018

Hepatic jaundice results from failure in the function of hepatocytes to take up, metabolize or excrete bilirubin.

Clinically, the jaundice tends to come on rapidly and is of an orange tint. Fatigue and malaise are common. Signs of hepatocellular failure may be evident.

Serum transaminases are increased. Serum albumin is reduced in chronic disease. Prothrombin time is prolonged and does not fall in response to parenteral vitamin K.