aetiology of phosphate deficiency
Last reviewed 01/2018
Causes include:
- reduced intake - chronic use of antacids such as aluminium hydroxide which causes excess binding of dietary phosphate
- increased loss:
- vitamin D resistant rickets - X-linked hypophosphataemia
- Fanconi's syndrome
- tumour induced - impaired renal conversion of 25(OH)D3 into calcitriol and phosphate wasting