overdose or severe toxicity
Last reviewed 01/2018
In the event of overdose or severe toxicity, cholestyramine or activated charcoal is recommended to accelerate elimination.
Cholestyramine (8 g tds for 24 hours) or activated charcoal (50 g every 6 hours for 24 hours) significantly reduces plasma levels by reducing the half-life from 2 weeks to 1 day.
This washout may be repeated if necessary.