prognosis
Last reviewed 01/2018
HLA matching is an important determinant of graft survival:
- 1 year graft survival
- if HLA identical then 95%
- if one mismatch then 90-95%
- if complete mismatch 75-80%
Cadaveric grafts have an average half-life of 8 years. This compares to a half-life of 20 years for HLA-identical graft from a living related donor.
Many deaths are from cardiovascular pathology which often is unrelated to transplantation or to immunosuppression.
Transplant related death is most commonly due to infection or malignancy.