clinical features
Last reviewed 09/2021
The clinical manifestations of renal bone disease are non-specific. The most common symptom is bone pain which is mainly in the legs, hips, knees, and lower back.
Other features may include:
- proximal muscle weakness - usually with normal muscle enzyme levels
- skeletal deformities of the spine and limbs - mainly in patients with osteomalacia
- tumoral and periarticular calcifications - causing swelling and acute joint pain
- pruritus - possibly from the high levels of calcium or phosphate in the skin