clinical indicators of secondary hypertension

Last edited 11/2018 and last reviewed 08/2021

A secondary cause of hypertension may be indicated by:

  • BP lability, episodic pallor and dizziness (pheochromocytoma)
  • snoring, hypersomnolence (obstructive sleep apnea)
  • prostatism (chronic kidney disease due to post-renal urinary tract obstruction)
  • muscle cramps, weakness (hypokalemia from primary aldosteronism or secondary aldosteronism due to renovascular disease)
  • weight loss, palpitations, heat intolerance (hyperthyroidism)
  • edema, fatigue, frequent urination (kidney disease or failure)
  • history of coarctation repair (residual hypertension associated with coarctation)
  • central obesity, facial rounding, easy bruisability (Cushing’s syndrome)
  • medication or substance use (e.g., alcohol, NSAIDS, cocaine, amphetamines)
  • absence of family history of hypertension (1)

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