lignocaine in cardiac resuscitation

Last reviewed 01/2018

Lignocaine is given in stable ventricular tachycardia, or after defibrillation in unstable ventricular tachycardia. It is not an adjunct to defibrillation. Its action is to block re-entry circuits, thus reducing ventricular ectopy.

Points of note include:

  • need to correct hypokalaemia before giving lignocaine
  • doses: see the relevant protocols
  • rapid hepatic elimination and rapid distribution
  • problems in liver disease, CHF or with drugs like cimetidine, propranolol and anticonvulsants.
  • iv access site will be rendered anaesthetic