location
Last reviewed 01/2018
Mast cells are found widely in connective tissue. However, they are concentrated in around small blood vessels in the skin, mucous membranes and capsules of organs.
They are numerous throughout the lymphoid system, particularly the thymus, but they are not present within the spleen.
Interestingly, the central nervous system connective tissue is devoid of mast cells: presumably an adaptive response to prevent allergic oedema.