nodular melanoma
Last reviewed 04/2022
Nodular melanoma is the most rapidly growing and aggressive variant of malignant melanoma.
- characterized by the absence of a radial growth phase
- seen on the trunk and limbs of patients in their fifth or sixth decade of life
- males are commonly affected than females (1)
- typically, it arises on apparently normal skin, has relatively little melanin and a rich blood supply
- patients have a symmetrical, raised, firm, often uniformly coloured and frequently non-pigmented nodule which continue to enlarge and become more raised (2)
- ulceration is common, giving a poorer prognosis.
Reference:
- (1) Markovic SN et al. Malignant melanoma in the 21st century, part 1: epidemiology, risk factors, screening, prevention, and diagnosis. Mayo Clin Proc. 2007;82(3):364-80
- (2) Cancer Council Australia/Australian Cancer Network/Ministry of Health, New Zealand (2008). Clinical Practice Guidelines for the Management of Melanoma In Australia and New Zealand