alternative options for women taking transdermal oestradiol only HRT in the form of (25/50/75/100) patches and do not require taking progestogen

Last edited 04/2022 and last reviewed 05/2022

Women taking transdermal oestradiol only HRT in the form of (25/50/75/100) patches and do not require taking progestogen (women who had a hysterectomy) can consider:

• Evorel (25/50/75/100)
• Estradot patches (25/50/75/100)
• Estradem patches (25/50/75/100)
• Femseven mono (50/75/100)
• Progynova TS (50/100)
  
  
• For a dose of 25 can use half a patch of 50. For a dose of 75 can use 3/4 of a patch of 100.
• Alternatively, could take a gel preparation such as Oestrogel or Sandrena:
  • Oestrogel:
    • If taking Evorel 25: Oestrogel one measure a day would give an equivalent
    • If taking Evorel 50: Oestrogel one measure twice a day would give an equivalent
    • If taking Evorel 75: Oestrogel three measures a day (2am and 1pm or vice versa) would give an equivalent
    • If taking Evorel 100: Oestrogel 4 measures a day (2am and 2pm) would give an equivalent
  • Or Sandrena gel:
    • If taking Evorel 25: 0.5mg Sandrena sachet a day would give an equivalent
    • If taking Evorel 50: 1mg Sandrena sachet a day would give an equivalent
    • Or Lenzetto three sprays (40 mcgm) equivalent to two measures of Oestrogel or 50 microgram patch

Reference:

• British Menopause Society. HRT preparations and equivalent alternatives Information for GPs and other health professionals (Accessed 27/4/22)