diuretic resistance

Last edited 03/2022 and last reviewed 03/2022

Diuretic resistance (DR) is defined as a failure to achieve therapeutically desired congestion relief despite using an appropriate diuretic dose

In heart failure patients, the prevalence of diuretic resistance (DR) is estimated as 20%-30% (1)

  • causes of diuretic resistance include poor adherence to drug therapy or dietary sodium restriction, pharmacokinetic issues, and compensatory increases in sodium reabsorption in nephron sites that are not blocked by the diuretic

Reference:

Related pages:

diuretics