granulocytes (neutrophils) in blood transfusion
Last reviewed 01/2018
granulocytes
Although clinical effectiveness of granulocytes (neutrophils) is debatable, it may be considered in patients with life-threatening soft tissue or organ infection with bacteria or fungi and low neutrophil counts, usually in the setting of severe, prolonged neutropenia after cytotoxic chemotherapy.
Two main granulocyte-rich components are used for transfusion:
- buffy coats derived from whole blood donations
- granulocytes collected by apheresis from individual donor
Granulocyte components must be ABO and RhD compatible and crossmatched with the recipient since it contains red cells (1)
Reference: