drug-induced hyponatraemia
Last reviewed 12/2021
Drug-induced hyponatraemia occurs in approximately 5% of outpatients and 15% of inpatients (1)
- in an Australian study the commonest drugs causing hyponatraemia were:
- indapamide
- sertraline
- amiloride/hydrochlorothiazide
- carbamazepine
- furosemide
- fluoxetine
- most patients with hyponatraemia are diagnosed incidentally on routine blood tests
Example causes of drug induced hyponatraemia:
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Diuretics
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Anticonvulsants
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ACE inhibitor
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COX2 inhibitor
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Hypnotics
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Sulphonylureas
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Proton pump inhibitor
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Hormonal analogue
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Antidepressants
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Recreational drugs
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Reference:
- Fourlanos S, Greenberg . Managing drug-induced hyponatraemia in adults.Aust Prescr: 2003;26:114-7.