lymphadenopathy (enlarged lymph nodes) in adults - NICE urgent cancer referral guidance
Last reviewed 08/2021
Lymphadenopathy
| Symptom and Specific Features | Possible Cancer | Recommendation |
| Lymphadenopathy (unexplained) in adults | Non-Hodgkin's lymphoma or Hodgkin's lymphoma |
Consider a suspected cancer pathway referral (for an appointment within 2 weeks) When considering referral for Hodgkin's lymphoma, take into account any associated symptoms, particularly fever, night sweats, shortness of breath, pruritus, weight loss or alcohol-induced lymph node pain When considering referral for non-Hodgkin's lymphoma, take into account any associated symptoms, particularly fever, night sweats, shortness of breath, pruritus or weight loss |
| Symptom and Specific Features | Possible Cancer | Recommendation |
| Lymphadenopathy (supraclavicular or persistent cervical), 40 and over | lung | Consider an urgent chest X-ray (to be performed within 2 weeks) |
| Symptom and Specific Features | Possible Cancer | Recommendation |
| Lymphadenopathy (generalised) in adults | Leukaemia | Consider a very urgent full blood count (within 48 hours) |
Reference:
NICE urgent cancer referral guidance
NICE urgent cancer referral guidance (guidelines with respect to presenting symptoms and signs)