haematological effects of antiviral nucleoside analogues

Last reviewed 01/2018

ANA's may cause:

  • bone marrow suppression
  • anaemia
  • thrombocytopaenia
  • leukopaenia

The association of bone marrow suppression with pancreatitis is a feature of ANA toxicity. This combination is also seen in an inherited mitochondrial disease called Pearson's marrow-pancreas syndrome.