laboratory events on cyclosporin A
Last reviewed 01/2018
Event: Value Action
Serum creatinine >30% above Reduce cyclosporin dose baseline by 50%
Serum creatinine >50% above Stop and seek advice baseline
Leucopaenia <3.5*10^9/l Stop & seek advice
Neutropaenia <2.5*10^9/l Stop & seek advice
Thrombocytopaenia <150*10^9/l Stop & seek advice
Macrocytosis >100 Check B12 and folate
Sequential falls >10% on Stop & seek advice in WCC or PMNs 3 occasions
Sequential falls >10% on Stop unless falls are from in platelets 3 occasions a high level, which is a response to treatment