laboratory events in monitoring penicillamine
Last reviewed 01/2018
| Event: | Value | Action |
| leucopaenia | <3.5 x 10^9/l | stop and seek advice |
| neutropaenia | <2.5 x 10^9/l | stop and seek advice |
| thrombocytopaenia | <150 x 10^9/l | stop and seek advice |
| sequential falls in WCCs or PMNs | >10% on 3 occasions | stop and seek advice |
| sequential falls in platelets | >10% on 3 occasions | stop unless falls are from a high level, which is a response to treatment |
| haematuria | trace or + | continue drug |
| haematuria | ++ or +++ | stop drug, check MSU, consider other causes, seek advice |
| proteinuria | trace or + | continue drug |
| proteinuria | ++ or +++ | stop drug, check MSU, 24-hour urinary proteint, seek advice |
Also check local prescribing guidance.