drug-induced syndrome of inappropriate ADH
Last reviewed 08/2022
The drugs most commonly implicated in SIADH are:
- thiazide diuretics
- vincristine
- vinblastine
- cyclophosphamide, at high or low dose
Others include:
- chlorpromamide
- carbamazepine
- phenothiazines
- tricyclic antidepressants
- clofibrate
- oxytocin
- vasopressin
- morphia
- barbiturates
- nicotine
Reference:
- McCarron MS et al (1995). Water intoxication after low dose cyclophosphamide. BMJ, 311,292.
- Felig P et al (2001) Endocrinology and Metabolism, McGraw-Hill.