aetiology

Last reviewed 01/2018

Localised areas of emphysema may be caused by:

  • congenital disorders

  • compensatory changes:
    • lung collapse
    • scarring
    • resection

  • partial bronchial occlusion:
    • foreign body
    • peribronchial lymphadenopathy
    • neoplasm

  • in rare cases a unilateral emphysema may occur due to bronchiolitis before the age of 8 years

  • smoking

Generalised:

  • idiopathic / primary

  • physiological (senile emphysema)

  • familial:
    • alpha 1 anti-trypsin deficiency
    • lower lobes more severely affected

  • associated with:
    • chronic bronchitis
    • chronic asthma
    • pneumoconioses