results
Last reviewed 01/2018
Patients withdrawn from digoxin therapy had:
- reduced maximal exercise capacity (median change in exercise time -96 s) compared with that of patients who continued to receive digoxin (change in exercise time +4.5 s) (p = 0.003)
- an increased incidence of treatment failures: 39% in the digoxin withdrawal group vs. 19% in the digoxin maintenance group, p=0.039)
- shorter times to treatment failure (p = 0.037)
- higher body weight (p = 0.044)
- higher heart rate (p = 0.003)
- lower left ventricular ejection fraction (p = 0.016)