intracellular calcium (effects)

Last reviewed 01/2018

Intracellular calcium may have a role in:

  • intracellular secondary messenger
  • exocrine and endocrine secretion
  • cell division
  • cell locomotion and shape change
  • stimulation of energy production
  • stimulation of muscular contraction

Many of these roles are due to the principle of calcium binding to regulatory or structural proteins e.g. tubulin, troponin C and calmodulin, in order to modulate their activity. Further, the binding of calcium to protein kinase enzymes can trigger the latter into phosphorylating other proteins. This is a means of initiating an amplified cascade.