peripheral nerves (thickened)

Last reviewed 01/2018

Thickened peripheral nerves should be palpated for if there is evidence of a peripheral nerve lesion, peripheral neuropathy, or a mononeuritis complex. The most accessible points are:

  • median nerve at the wrist
  • ulnar nerve at the elbow
  • common peroneal nerve at the head of the fibula

Causes of thickening may be remembered by the mnemonic HAGALO:

  • Hypertrophic neuropathy - a rare autosomal dominant condition
  • Acromegaly
  • Guillain Barre - if relapsing and remitting disease
  • Amyloid
  • Leprosy
  • Others - e.g. neurofibromatosis, diabetes, sarcoidosis, Charcot-Marie-Tooth disease