switching antidepressant (mirtazapine to agomelatine) in adults
Last edited 03/2023 and last reviewed 03/2023
Mirtazapine to agomelatineCross-taper
- cross-tapering can usually be undertaken cautiously over 2 to 4 weeks, the speed is determined by individual tolerability
- is limited experience with this switch so extra caution is required. Although interactions are not expected, agomelatine is not expected to mitigate discontinuation reactions from stopping mirtazapine.
Reference:
- NHS Specialist Pharmacy Service (February 2023).Mirtazapine to other antidepressants: switching in adults
summary advice - switching from mirtazapine to another antidepressant