treatment of MODY
Last reviewed 12/2022
treatment
seek expert advice.
GCK - MODY
- general consensus is that the majority of these patients do not require treatment since insulin or oral hypoglycaemic agents has little effect on glycemia in this group
- however in pregnancy insulin may be required to prevent excess fetal growth
HNF1A-MODY and HNF4A-MODY
- low dose sulfonylureas are recommended as first line treatment for patients with HNF1A/HNF4A-MODY, however most patients will progress to insulin treatment with time
- a short-acting sulfonylurea such as nateglinide may sometimes be used as an alternative
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