situations which require to test for antiphospholipid antibodies (APS)
Last reviewed 01/2018
The following are considered as indications for testing for antiphospholipid antibodies:
- thrombosis
- arterial thrombosis before the age of 50
- unprovoked venous thrombosis before the age of 50
- recurrent thrombosis
- thrombosis at an unusual site
- patients with both arterial and venous thrombotic events
- any patient admitted with thrombotic microangiopathy of unknown aetiology
- obstetric manifestation
- one or more unexplained fetal loss after 10 weeks gestation
- unexplained severe intrauterine growth restriction
- early or severe pre-eclampsia
- three or more spontaneous miscarriages before 10 weeks of gestation
- patients with SLE
- at baseline
- repeat testing before pregnancy, surgery, transplantation and use of oestrogen containing treatments or in the presence of new neurological, vascular or obstetric event (1)
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