calculation of warfarin maintenance dose based on rapid anticoagulation regime with 10mg initial dose
Last edited 04/2019
This is based on the INR taken on the morning of day 4, ie after 3 doses of warfarin. Check with local guidance before prescribing.
Example guidance:
| INR |
Predicted maintenance dose
|
|
< 1.4
|
>8 |
| 1.4 | 8 |
| 1.5 | 7.5 |
| 1.6-1.7 | 7 |
| 1.8 | 6.5 |
| 1.9 | 6 |
| 2.0-2.3 | 5.5 |
| 2.4-2.6 | 4.5 |
| 2.7-3.0 | 4 |
| 3.1-3.5 | 3.5 |
| 3.6-4.0 | 3 |
|
4.1-4.5 |
miss out next day's dose then 2mg per day |
| >4.5 | miss out next two days' dose then 1mg per day |
Ref: Prescribers' Journal (1997), 37 (3),173-9.