treatment

Last reviewed 01/2018

Patients may respond to treatment with vitamin B6 in doses of up to 500 mg/day. It may be necessary to add supplements of folate and vitamin B12.

If homocysteine levels do not fall then restriction of dietary methionine to 10-40 mg per day may be required.

The conversion of homocysteine back to methionine may be promoted by giving betaine or choline.