Loeffler's endocarditis
Last reviewed 01/2018
Eosinophilic endomyocardial disease is characterized by:
- endomyocardial fibrosis
- a high incidence at temperate latitudes
- large mural thrombi
- eosinophilia with infiltration of organs especially the heart (causing restrictive cardiomyopathy)
- rapid fatality
This disease is closely related to the African condition of endomyocardial fibrosis (qv).
Treatment measures include:
- suppression of eosinophilia e.g. prednisolone or hydroxycarbamide (former British Approved Name, hydroxyurea)
- digoxin
- diuretics