vigabatrin and visual field defects

Last reviewed 01/2018

  • diplopia is a well-known side effect, in common with other anti-epileptic drugs (1)

  • visual field defects (e.g. tunnel vision) have been reported whilst on vigabatrin therapy. The onset of the visual field defect varies from one month to several years after starting vigabatrin. Visual field loss associated with use of vigabatrin appears to be irreversible, even after cessation of therapy

Reference:

  • Current Problems in Pharmacovigilance (1999), 25, 13.