interleukin-8

Last reviewed 01/2018

Interleukin 8 is a low molecular weight cytokine consisting of a relatively short peptide chain. It is produced in:

  • mononuclear phagocytes
  • lymphocytes
  • endothelial cells
  • fibroblasts
  • neutrophils

Its effects are mainly pro-inflammatory and include neutrophil activation, chemotaxis and degranulation.