disuse / immobility

Last reviewed 01/2023

  • reduced physical activity increases the rate of bone loss in both experimental animals and humans

  • osteoporosis may occur in circumstances such as:
    • prolonged bed rest
    • paralysis
    • excessive immobilisation of a fracture
    • astronauts

  • weight-bearing exercise, especially in the second decade of life, protects against subsequent osteoporosis