SOLVD - prevention arm
Last reviewed 01/2018
This multicentre, randomised, double-blind, placebo-controlled trial enrolled 4228 patients with reduced left ventricular function (ejection fraction <35%) but without symptomatic heart failure.
The addition of enalapril to the conventional heart failure treatment resulted in a significant 37% decrease in the incidence of heart failure.
Reference:
- SOLVD Investigators. (1992). N Engl J Med. 327, 685-691.