lysosomal constituents

Last reviewed 01/2018

The lysosomes of various cells within the inflammatory response supply a number of active agents:

  • neutrophils:
    • specific granules:
      • lactoferrin
      • lysozyme
      • alkaline phosphatase
      • leukocyte adhesion molecules, promoting movement
    • azurophilic granules:
    • myeloperoxidase
      • lysozyme
      • acid hydrolases
      • cationic proteins
      • neutral proteases
  • monocytes and macrophages:
    • acid hydrolases
    • neutral proteases
    • plasminogen activator
  • platelets, from alpha granules:
    • fibrinogen
    • factor V
    • platelet factor 4
    • von Willebrand factor
    • platelet derived growth factor