cortisone

Last reviewed 01/2018

Cortisone is a glucocoritcoid produced in the zona fasciculata of the adrenal cortex. It has approximately 80% of the anti-inflammatory and sodium-retaining potency of hydrocortisone.

Physiologically, it is produced by the oxidation of cortisol. Synthetic cortisone is not widely used because of its significant mineralocorticoid effects.