investigations

Last reviewed 01/2018

Investigations include:

  • chest X-ray
  • white cell count is normal or mild leukocytosis - with increase in early granulocyte forms; rarely above 15 x 10^9/l.
  • hyponatraemia and hypoalbuminaemia in up to 50%
  • abnormal LFT's
  • gram stain does not detect the organism
  • urine testing may reveal haematuria

Diagnosis is confirmed by:

  • urinary antigen detection
  • change in antibody titre, with a four fold increase at 2 to 5 weeks
  • immunoflourescent staining of the organism in the pleural fluid, sputum or bronchial washings