switching antidepressant (vortioxetine to trazodone) in adults
Last edited 03/2023 and last reviewed 03/2023
Vortioxetine to trazodone
- is limited experience with this switch so extra caution is required to avoid serotonin syndrome.
- cross-tapering can usually be undertaken cautiously over 2 to 4 weeks, the speed is determined by individual tolerability
- alternatively, stop vortioxetine; wait for a period before starting trazodone. Clinicians should decide the duration of the washout period on a case-by-case basis
Reference:
- NHS Specialist Pharmacy Service (February 2023). Vortioxetine to other antidepressants: switching in adults
summary advice - switching from vortioxetine to another antidepressant