switching antidepressant (vortioxetine to selective serotonin reuptake inhibitors (SSRIs)) in adults
Last edited 03/2023 and last reviewed 03/2023
Vortioxetine to selective serotonin reuptake inhibitors (SSRIs)
- is limited experience with this switch so extra caution is required to avoid serotonin syndrome.
- a direct switch, i.e. stopping one antidepressant and then starting the new antidepressant the following day, is normally possible
- alternatively, stop vortioxetine; wait for a period before starting the SSRI. Clinicians should decide the duration of the washout period on a case-by-case basis.
Reference:
- NHS Specialist Pharmacy Service (February 2023). Vortioxetine to other antidepressants: switching in adults
summary advice - switching from vortioxetine to another antidepressant