Holmes tremor
Last edited 05/2022 and last reviewed 05/2022
- described by Gordon Holmes in 1904 as a 3-4 Hz coarse tremor of the arms present at rest and exacerbated by action and posture
- tremor tends to involve the proximal musculature
- is secondary to vascular or traumatic lesions in the midbrain and in multiple sclerosis
- has variable response to medications including levetiracetam, levodopa and trihexyphenidyl
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