drug - induced testosterone deficiency (TD) in a male

Last edited 05/2018

Medications associated with an increased prevalence of TD

Medications associated with an increased prevalence of TD:1-5

• oral glucocorticoids
• opioids
• antipsychotics
• anticonvulsants
• androgen deprivation therapy
• antiretroviral therapy
• chemotherapy + radiation
• methadone maintenance therapy

References

• 1. Khera M, Adaikan G, Buvat J, et al. Diagnosis and Treatment of Testosterone Deficiency: Recommendations From the Fourth International Consultation for Sexual Medicine (ICSM 2015). J Sex Med 2016;13:1787-1804.
• 2. Dohle GH, Arver S, Bettochi C et al. Guidelines on Male Hypogonadism. European Association of Urology 2017. Available at: http://uroweb.org/guideline/male-hypogonadism/ (Accessed May 2018).
• 3. Bhasin S et al. Task Force, Endocrine Society. Testosterone therapy in men with androgen deficiency syndromes: An Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2010;95:2536-59.
• 4. Lunenfeld B, Mskhalaya G, Zitzmann M, et al. Recommendations on the diagnosis, treatment and monitoring of hypogonadism in men. Aging Male 2015;18:5-15.
• 5. Hassan J, Barkin J. Testosterone deficiency syndrome: benefits, risks and realities associated with testosterone replacement therapy. Can J Urol 2016;23:20-30.