physiological jaundice in the neonate
Last reviewed 01/2018
In the newborn increased erythrocyte breakdown or decreased liver function can both cause physiological jaundice. This condition appears at two or three days old and begins to disappear towards the end of the first week.
Pathological jaundice is more severe and prolonged in preterm infants. Also, conjugation may be limited by hypoglycaemia and hypoxia. An increased enteric absorption of bilirubin may occur if the infant has a bowel obstruction or an ileus.
The condition is asymptomatic in the neonate but may reach toxic levels in the preterm infant.
Management is dependent on level of bilirubin.