nRNP autoantibody
Last reviewed 01/2018
This is antibody to a cytoplasmic ribonuclear protein complex
nRNP antibody
- target U1-RNP
- positive in 15% systemic sclerosis
- clinical association
- overlap features of SLE, arthritis
- associated with mixed connective disease and SLE with particular features (arthritis, myositis, Raynaud's phenomenon - also association with HLA-DR4 and HLA-DQw8)
- overlap features of SLE, arthritis
Reference:
- 1) Arthritis Research Campaign (2010). Topical Reviews - Systemic sclerosis and related disorders.