rifampicin
Last reviewed 01/2018
Rifampicin is a drug that is indicated in:
- tuberculosis
- meningococcal meningitis prophylaxis
- leprosy
Cautious use is required:
- it discolours soft contact lenses
- reduce dose in:
- hepatic impairment
- alcoholism
- pregnancy
- users of the oral contraceptive pill should take additional contraceptive precautions
Contra-indications to its use are:
- jaundice
- porphyria
Side-effects of rifampicin include:
- shortness of breath
- collapse and shock
- acute renal failure
- thrombocytopenic purpura
- gastrointestinal symptoms
- influenzal syndrome
- hepatic reactions with alterations of liver function, jaundice, urticaria and rashes
- urine, saliva and other secretions coloured orange-red
Routes of administration:
- oral:
- tablets
- capsules
- syrup
- i.v. infusion
The summary of product characteristics should be consulted before prescribing this drug.