cerebellar tremor
Last edited 05/2022 and last reviewed 06/2022
Cerebellar tremor presents as a unilateral or bilateral, low-frequency intention tremor(1).
- is a slow, broad tremor of the extremities (2)
- it occurs at the end of a purposeful movement
- it may be caused by damage to the cerebellum resulting from stroke, brainstem tumor, or multiple sclerosis.
- cerebellar lesions produce kinetic tremor on the ipsilateral side of the body
- finger-to-nose testing results in worsening tremor as the finger approaches the nose.
- it is a 6-8 Hz tremor that is of variable amplitude.
Clinical features include:
- aggravation by change in posture and movement
- terminal accentuation, i.e. worse at end of movement
- relief by rest
- major sites for this tremor are the limbs, trunk and head
- associated features of dysmetria, ataxia and nystagmus
A cerebellar tremor is caused by a lesion of the red nucleus. It may occur as part of Benedikt's syndrome.
Management:
- seek expert advice
- possible medications to treat cerebellar tremors include topiramate and ondansetron (3)
Reference:
- (1) Sharon Smaga. Tremor. Am Fam Physician 2003;68:1545-52,1553
- (2) Tremor fact sheet. National Institute of Neurological Disorders and Stroke National Institutes of Health.2007
- (3) Frei K, Truong DD. Medications used to treat tremors. J Neurol Sci. 2022 Apr 15;435:120194. doi: 10.1016/j.jns.2022.120194. Epub 2022 Feb 19. PMID: 35279634.